Symptoms such as these may be associated with an increased risk for suicidal thinking and behavior and indicate a need for very close monitoring and possibly changes in the medication. Changes in body weight during pharmacological treatment of depression. Это приводит к непропорциональному повышению концентрации пароксетина в плазме крови и изменению фармакокинетических параметров с появлением нелинейной зависимости. Для некоторых больных с недостаточной эффективностью при приеме 20 мг дозу можно постепенно повышать на 10 мг/сут, в зависимости от клинического эффекта, до 50 мг/сут.Лица пожилого возраста. However, further efforts to develop animal models to characterise and consolidate the linkage between stress and obesity are needed. The risk of seizures is also related to patient factors, clinical situations, and concomitant medications that lower the seizure threshold.
Different forms of obesity as a function of diet composition. Pregnancy Advise patients to notify their healthcare provider if they become pregnant or intend to become pregnant during therapy. The presence of food did not affect the peak concentration or area under the curve of bupropion.
Relationship between the prevalence of depressive symptoms and metabolic syndrome. Wellbutrin XL treatment may lead to decreased alcohol tolerance. However, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms.